-Boyfriend from Friday Night Funkin' (brother)
--By extension, Ritz (adopted brother)
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Sonic the hedgehog (cousin)
-- by extension, uncle Chuck, Miles "Tails" Prower, Manic, Sonia, and probably 23 characters from the Archie comics I don't know about -
Franziska von Karma (sister)
-- By extension, Miles Edgeworth (adopted brother), Phoenix Wright and Maya Fey (in-laws; also Mia and Pearl Fey by extension), Trucy Wright, Athena Cykes, and Kay Faraday (nieces), Sebastian Debeste and Apollo Justice (nephews) -
Mike Hatsune (father)
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the IBM 7094 (grandfather)
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Minecraft (creation (child?))
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Megaman (same person, just depends on whether she has the super crown)
-- By extension, Dr. Light (creator/father), Roll (Sister), Blues (Brother), X (Brother), and arguably all of the other robot masters Dr. Light has ever created (siblings) -
I will update this post if I receive more information -- currently investigating potential link to Norville "Shaggy" Rogers, who may potentially be related to Roll Light. Any information on this potential thread would be greatly appreciated