No one can truly stop you from opening the console menu and changing your character's gender. If any NPCs show disgust at your action, the command to acquire the spell Enemies Explode is "addspell 014720".
Joke and fake loading screens and screenshots from The Elder Scrolls IV: Oblivion, run by @ChrisOfTheDead.
General links and the actual Oblivion mod made from these jokes in my Carrd page:
