Here's what I'm rolling with right now for my Agatha list. Black Bolt+Stature and Silk+Miles Morales gives me a good shot of playing two cards on Turn 6, but there are other packages you can include. These two give a real Goldilocks sequence of Silk -> Sif discards Agatha -> Jubilee/Iron Lad -> Black Bolt on Silk's location -> Miles Morales+Stature+Ghost Rider.
Quinjet+Loki
Daredevil+Gamora/Prof X
Master Mold+Ronan
If I had Corvus that would likely be a good inclusion as well. Or Makkari. I would not sleep on the extra 4 points in a deck that ends up actually playing so few cards.