I know I'm not saying anything new, but "even if there are more benefits than downsides, having to Take/Do A Medicine Thing is always a net negative that should be avoided at all costs" is such a tangled and pervasive mindset that I think I was thirty-five before the little bubble popped over my head and I really got that I had never been making choices that would prevent me from attaining some kind of perfect form. It was never there. The best thing we can do is make ourselves comfortable with what we have.
And not in a "this is as good as it gets, deal with it" sense but rather, when I was younger I was always receiving the impression that if I just didn't do anything too Permanent I wouldn't have anything to regret. And now I'm a few months shy of forty, and I have the body I was probably always going to have when I was twenty. I can do lots of things to change it: I'm on hormones, I'd like to work out because I miss being physically strong, I can get tattoos or piercings or dye my hair. But for a long time, I didn't realize how much I just took for granted that it was good to avoid making commitments to my body. I knew it was going to experience permanent, unavoidable changes, but somehow I just internalized that the obvious goal was to not be responsible for any of them of my own free will.
When people say shit like, "You'll have to be on medication for the rest of your life!" or otherwise act like they're doing something helpful by judging other people's choices about their own bodies, all I can hear is the fear of body permanence. If you do the wrong things, you'll never attain your perfect form!! We are all always one superfood or sleep regimen or exercise away from being our best selves, except that the only one who has to live in your body is you and your best self is the one that makes you happy because that's literally all there is.
There is no achievement for avoiding the things that make our bodies better homes for us! Being happy is the reward!