Quick thread of recent studies showing, again, with ever-increasing confidence, that risk of long-term post-acute COVID symptoms and reinfections increase with multiple infections! Please keep wearing N95-grade masks or elastomeric respirators, reduce risk by reducing time spent in large gatherings & travel, and encourage others in your life to do the same! Please!
Click here for the text version of this chost, because twitter inlining is broken and shit, just like twitter
“We report a consistent increase in the risk of persistent symptoms after reinfection compared to first infection. All post-acute symptoms mentioned in the WHO clinical case definition appeared more common after reinfection than after a 1st infection”
‘RoBuSt HyBriD iMmuNiTy’ 🤪
Yet another study showing that more infections = more morbidity. Can we like warn people maybe? Feels like something people might want to know.
https://www.nature.com/articles/s41467-023-42726-0.pdf
“Escalation of commitment: A human behavior pattern in which an individual or group facing increasingly negative outcomes from a decision, action, or investment nevertheless continue the behavior instead of altering course.”
¯_(ツ)_/¯
Oops.
“Our results show that the first episode of SARS-CoV-2 infection induces a significant increase in neutralizing titers in triple vaccinated individuals and that previous SARS-CoV-2 infection compromise significantly the neutralization response induced by reinfection”
(inlined tweet) https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.29225
Oops again.
“We found that those who had battled the BA.1-2 variant of Omicron in early 2022 had a 30-fold higher risk of contracting the BA.5 variant later in the year. That was exactly the opposite of what we, or anyone, would have predicted.”
A startling discovery: Older adults who previously had COVID are at higher risk of reinfection. More than ever, staying up to date on boosters is the best way to protect against illness, say Dawn Bowdish and Andrew Costa.
https://ow.ly/9XcJ50PGT59
So much oops.
“Our findings suggest that COVID-19 contributed to the 2022 surge of RSV cases in young children through the large buildup of COVID-19-infected children and the potential long-term adverse effects of COVID-19 on the immune and respiratory systems.”
Hey, remember when a massive wave of RSV hit kids in 2022?
You know, the one blamed on “immunity debt” by economists who couldn’t stay in their lane or stop writing horror fanfiction about the years-delayed impact of lockdowns that never happened?
Surprise! COVID caused it.
(Quote from a study linked in a reply of Tweet 6's Inlined Tweet:)
In conclusion, our study supports that prior COVID-19 infection was associated with a significantly increased risk for RSV infection and may have been a driving force for the 2022 surge of severe paediatric RSV cases in the USA and this should be further investigated. Prevention measures such as vaccines would be beneficial in preventing both COVID-19 infection and COVID-19-associated diseases including RSV infection.
Throwback oops.
“The evidence shows that reinfection further increases risks of death, hosp and sequelae in multiple organ systems in the acute and postacute phase. Reducing overall burden of death and disease due to SARS2 will require strategies for reinfection prevention.”
Importantly,
Reinfection increased the risks of death, hospitalization and organ injury in the acute and post-acute phase
and
the elevated risks remained evident at 6 months after reinfection
Reinfection increases the risk of acute and #LongCovid
https://www.nature.com/articles/s41591-022-02051-3
“[Scientific] uncertainty is manufactured to create the latitude for implementing disease control policies that run counter to broad societal values.”
I wrote a thread about this a while ago. We lack values consensus. Uncertainty is manufactured to create the latitude for implementing disease control policies that run counter to broad societal values (eg don’t kill people, don’t sicken children, etc)
https://twitter.com/DFisman/status/1591972576104173568 (Tweet 8's Inlined Tweet's Inlined Tweet. You can click this one yourself)
Bonus oops.
The increase in cognitive disability among people at the prime of their working lives is extremely worrisome. The fact that this trend is not levelling off should keep policy makers (and everyone else) up at night.
https://twitter.com/loscharlos/status/1724164481281032414 (Tweet 9's Inlined Tweet's Inlined Tweet, you can click this one yourself)
... and done.
First and last time I'm doing something like this, because JCVS, I'm exhausted, and this shit just sprawls
