Yeah, the "God made wheat but not bread" argument against transphobia is pretty good, but have you considered taking the Talmud's tack and just calling them fucking stupid
[Rabbi Elazar, riding on his donkey and feeling full of himself] happened upon an exceedingly ugly person, who said to him: "Greetings to you, my rabbi," but Rabbi Elazar did not return his greeting. Instead, Rabbi Elazar said to him: "Worthless person, how ugly is that man. Are all the people of your city as ugly as you?" The man said to him: "I do not know, but you should go and say to the Craftsman Who made me: How ugly is the vessel you made." When Rabbi Elazar realized that he had sinned and insulted this man merely on account of his appearance, he descended from his donkey and prostrated himself before him, and he said to the man: "I have sinned against you; forgive me." The man said to him: "I will not forgive you go until you go to the Craftsman Who made me and say: How ugly is the vessel you made."