i have a bad reaction to spiro that slowly builds over months, and i suspect it's the inactive ingredient lactose monohydrate causing the problem. i am experimenting with taking lactase about ten minutes before each dose of spironolactone. it's only been a few days so results are inconclusive. what is striking me though, is that every time i take lactase, i get a sensation of immense relief a few minutes later. just from the lactase. what's that about? i completely removed dairy from my diet months ago.