reply to this post with one of these characters and i'll do a run as that character and i'll tell you how it went
@wiredwhimsical suggested robot. (weapon drops are 1 tier higher, can eat weapons for health/ammo pickups)
this run felt like it had bad mutation choices, only things which stood out were rhino skin (+4 max HP) and trigger fingers (reduces reload time on kill), everything else was just kinda mid. i guess bolt marrow (bolts change trajectory to home in on enemies) isn't that bad either? maybe i should make a mutation tier list to show my thoughts.
then on 5-2 i accidentially opened the crown vault, decided i'll just pick a random crown to make it interesting, and chose crown of destiny (you only get one mutation option for mutations, but you get a free mutation right away).
what killed me at the end there, though, was an ammo crunch! i had super crossbow + energy sword, but super crossbow didn't have any ammo. had a standoff with a single guardian dog which blocked me off in a hallway in 7-1 with just my energy sword and nearly lost to that. i had some bolts for 7-2, but not enough.
