yes, as in the interactive fiction/games tool
when I was job hunting1 I needed to put up a personal site fast, but the idea of using one of those Here's My Hero Image and Infinite Scroll Portfolio and a Bunch of Random Icons templates made me aesthetically sick. I also have a lifelong love of using tools for things they are not really designed for2.
This isn't zero effort exactly; in addition to purchasing/configuring a web host, contorting a twine into a site-site requires some hacking-out of game state and fiddliness with CSS and image hosting, for certain things you may need to edit the generated HTML file manually, and I need to figure out whether RSS is possible. But adding and editing stuff is just a matter of adding/editing passages, and the perversity of it amuses me.
A similar tool is Decker for Hypercard stack-like sites; I haven't messed around with it but I know of at least a few personal sites using it.
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that was rough but happily I am no longer job hunting
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but not disallowed or discouraged: "Anything you create with [Twine] is completely free to use any way you like, including for commercial purposes."
yep, everything in twine allows javascript! some story formats make it easier than others but even in the less javascript-friendly formats (e.g., harlowe) it is very possible if you know it.
chapbook fwiw is my current recommendation, seems most actively maintained, and is best imo in terms of default presentation/responsive design
Adding this as yet another thing to check out when I have spoons. (I'm commenting on them because that'll make it easier to find when I'm filtering my old posts)