One of the smartest tools I've written for myself on this is a little script that searches the entirety of my test transcripts in the skein.
So for example, I am writing a response that I skipped writing for the earlier version, only saying "TODO: blah blah blah". Because of reasons I am filling all of those back in.
So, having a script means that I can search for that temporary thing I wrote, and then find out which tests had that text in them, so rather than re-running all of my tests and taking an hour, I can just hit the ones that are necessary.
I'm feeling like this may become a dev diary topic but I'm explicitly pushing this off to after this major release.