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autumn-gales
@autumn-gales

hey just bc Ive been dealing with a lot of trans girlies w this issue. If your doctor ever prescribes weekly injections, ASK FOR CYPIONATE, NOT VALERATE.

If valerate is your only option, then MAKE SURE YOUR DOCTOR PRESCRIBES YOU ENOUGH FOR 4 or 5 DAY INJECTION CYCLES.

Weekly injections (every 7 days) with estradiol valerate leaves you with long periods of REALLY LOW HORMONE LEVELS IN YOUR BODY which can lead to symptoms like LOWERED MOOD, AND DEPRESSION SYMPTOMS.

So far, it's been a common experience that doctors prescribing estradiol injections have NO IDEA WHAT THEY'RE DOING and I've seen some friends deal with adverse effects and worsened mental health bc they don't know this.

So, unfortunately, it falls to us to learn and spread this info ourselves.


Bwarch
@Bwarch
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What the lady says be so true. These graphs as generated by: https://transfemscience.org/misc/injectable-e2-simulator/. The lowest valleys will be your worst moods potentially, and cypionate just overall smooths everything out and keeps your levels up very well.

Me and Autumn have talked before about this and in fact I'm on 7 days of valerate. My mood is really decently low and disastrous, and my next gender appointment I'll be discussing all this with my gender doc. Get 5 days of valerate if you have to, but 5 days of cypionate is better. And enanthate is the best of all with its long life cycle, just rare to get prescribed. https://hrtcafe.net/

I've been trying to also add on some leftover oral estrogen on those two low days, but, I don't recommend it precisely and it hasn't helped toooo much. (Honestly I just have a bit of disastrous life/depression in general but, u kno)


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in reply to @autumn-gales's post:

If you switch to cypionate or go on a more frequent injection schedule (someone else either rechosted or commented on here that they inject on mondays and thursdays) you may be able to dodge feeling low on injection day altogether. But also!! ymmv amd everybody's bodies are different.

Some friends were having the problem of feeling really bad when their hormone levels dropped too low.

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