One major group guilty of this is cis weebs, and it kind of goes in two different ways.
One weeb fiction archetype is the sexually aggressive "futanari" (a.k.a. futa), who are typically women with large penises and breasts. They may or may not have vaginas as well. Western depictions, which have become widespread in recent years, differ a bit from futanari in Japanese hentai, who are not so uniformly sexually aggressive. (I can't help but feel that widespread false ideas about trans women being sexual aggressors may have influenced this).
Weebs are often insistent that futanari have nothing to do with trans women, though even Wikipedia says, "American transgender pornography that was introduced to Japan influenced the earliest futanari works, which were drawn by artists including Kitamimaki Kei." Within many narratives, the futanari are presented as simply being born like that, and any subjects such as trans identity and gender transition are carefully avoided. This means that futanari in these cases are not really AMAB or AFAB, but assigned some type of other sex at birth. This seemingly assuages the fears of male weeb chasers that liking futanari might qualify them as gay.
In a Western online context, futanari have come to serve the role of trans woman as top, paired with an questionable insistence that these fictional women with penises have absolutely no relation to women with penises in the real world.
Another weeb fiction archetype is the "femboy", an AMAB individual with a feminine gender presentation and style of dress who explicitly is identified as a boy. This bears a close resemblance to a term previously popular in weeb culture, that of the "trap". Both of these have been used as a rough translation of "男の娘", a pun in Japanese used to describe (largely fictional) men or boys with a feminine presentation.
As with the futanari, there is often an insistence that femboys have absolutely nothing to do with trans women or transfeminine people. Unlike futanari, femboys do not represent a way to avoid being seen as gay for cis men, but rather serve as a way to fetishize feminine individuals with penises while maintaining an ability to reject trans identity outright.
In some cases, there are "border wars" of a sort, in which the classification of characters are debated hotly on the internet. One example of this is Bridget from Guilty Gear, who was historically considered by many weebs to be a canonical example of a "trap" or "femboy", but in recent years has been explicitly identified by her creators as a trans girl. In a demonstration of how many weebs wish to outright reject trans identity, numerous cis weebs online were furious at this identification of Bridget as a trans woman.
Unlike futanari, femboys are most often presented as natural bottoms, and thus in some contexts serve as a substitute for trans woman as bottom. In a Western context, particularly in the last few years, femboys and futas have often been paired up, serving as bottom and top respectively. In these narratives, there is often a strangely artificial divide enforced between these two categories, and once again there is a careful effort to avoid bringing up trans identity or gender transition. In some sense, this pairing serves as a form of t4t distorted beyond recognition, bending over backwards to avoid mentioning real issues in the real world.
None of this is to say that enjoying works with futanari or femboys is inherently bad, or that the terms are always used in problematic ways, but rather that it's worth considering how these ideas do or do not relate to the real world.
