C:\Program Files (derogatory)\

Recovering comedian, polymorphic fox-shaped lava monster, self-appointed Sheriff of Saturn, singing voice of the Wingdings font.
C:\Program Files (derogatory)\
This is actually funny and I don't know why
(Please tell me (which will ruin the joke) but I'll actually know and (recursion))
it's a combination of Program Files {x86}, the directory in which 32-bit programs will install to in 64-bit Windows, and the use of (derogatory) to indicate that the thing tagged is meant to be read in a derogatory tone (though it's often used in a more lighthearted or joking manner).