Hiroshi Aoyagi: the protagonist of RGG Tactics. A Majima Family man with a knack for turning restaurants into licenses to print money. General manager of Kiwami Cafe in Kamurocho and later Neko-Kai Cafe in Sotenbori. A little guy with a big mouth. Loyal to a fault and stubborn as shit. Nishida's oath brother. Later forced to be Majima Construction's chief of safety and compliance and he hates every second of it.
Eiji Yamaoka: A Nishikiyama Family hitman who presents himself as a protective big brother to Aoyagi, but neither Aoyagi nor the audience are fooled by his bullshit. Clean and methodical on the clock, charming and outgoing on his own time, rarely seen without at least one pretty girl on his arm.
Yusuke Kuroshi/Homare Nishitani II: Current patriarch of the Kijin Clan, retainer to the Omi Alliance chairman, chairman of the Sotenbori Civic Association's Board of Directors, and legendary info broker. By all appearances, the exact opposite of his predecessor. Cold, calculating, refined, sometimes cruel, always in control. Or... almost always. If you've read "It's All About the Bit" you've met him.
Keiichi Sugihara (Kei-chan): Nishitani II's better half, Civic Association member, owner of a video game store with a slightly illegal console chop shop in the back room, tech hobbyist who believes in better ass-kicking through technology.
Nobuaki Chiba: Kijin Clan lieutenant. Very intimidating if you don't know him. Kind of intimidating if you do know him, but for the most part he's Just A Guy who likes beer and fried shit and sportsball and throwing some good old fashioned hands in the street. Aoyagi's first friend in Sotenbori.
Shigeo "Doc" Nakamura: A doctor working for the Sotenbori Civic Association. Nobody's a hundred percent sure he actually has a license to practice but he does good work and he doesn't ask uncomfortable questions.
Shiori Hanada: A hostess at Club Sunshine who personally puts the fear of God into some asshole who's been snapping covert hostess foot pics under the tables and selling them on the street. She later goes to work at Cabaret Grand after Sunshine's current owner becomes too shitty a boss to stand.
Daikichi "b0ngl0rd69" Tomita: A friend(?) of Sugihara's who makes him look downright normal about games by comparison. Walks around Sotenbori with an honest to God gunblade. Is absolutely aware that the number in his handle has some... connotations in English.
Akemi "Crystal Star Sapphire" Sakurai: A hostess at Jewel in Kamurocho who moonlights at a magical girl-themed cosplay bar. She is an engineering major at Touto University who combines her technical knowhow with her prop-building skill to create ice-based weapons that are as dangerous (and possibly illegal) as they are pretty.
Minoru "Unlucky" Uchida: A string of poor life choices starting on the morning of his 42nd birthday have rendered him the unluckiest yakuza alive. Every single time his turn comes up, he will get hit by a random environmental hazard--and usually one with splash damage. His only real use in battle is to be sent into the middle of enemy formations like a laser-guided misfortune missile.
Torahiko Kogawa: Cat cafe mogul and terrible, horrible, no-good, very bad person. The antagonist of the Cat Cafe Grand Prix sideplot.
Yashiro Noguchi: CEO of Millennium Holdings in Sendai, currently being blackmailed by someone connected to his former boss in Sotenbori along with a number of his former associates.
Miyuki: Mysteriously dumped at the animal shelter in the dead of night and subsequently entrusted to Aoyagi's care as his first cafe cat. Pure white with the prettiest deep blue eyes. Magnificently fluffy, amazingly sociable, and stone deaf.
Ryo Amon: Personal chef to the Amon Clan, challenges Aoyagi and his crew to a cooking battle at the end of the Chef League sideplot.
Gen Amon: Leader of a breakaway sect of the Amon Clan, takes issue with certain rules of engagement the Amon Clan adheres to. He and his team are the requisite RGG Secret Boss Battle. Yes, Aoyagi gets not one but TWO rounds of Amon Clan Bullshit to deal with in this game.
Nyamon: A huge stocky black cat with God tier stats, who mysteriously shows up at the cat cafe shortly after you beat Gen Amon's team. While most of the cafe cats will let you put cute accessories on them, Nyamon will hiss at you if you attempt to swap his aviator shades out for something else.