a few weeks ago we thought we’d finally identified one of the core issues with the physical symptoms (POTS, PEM). basically (if you know your basic biology) the input to the krebs cycle is pyruvate which is created from glucose (keeping it simple). when you run out of abundant oxygen or need energy fast your body converts pyruvate into lactate. it does this with an enzyme called LDH. my recent blood tests revealed my LDH to be off the scale low 
everything else seems fine (though likely there is literally brain cruft build up slowing me down) but this was an issue. also it probably was causing a lot of diabetes like symptoms as my body destroyed itself to fuel muscles and not processing much glucose.
read more for treatment details
a few weeks ago i started a supplement that should metabolize into one of the inputs to the LDH enzyme as well as encourage production of it.
while i can’t say for certain, my calves have started feeling sore!! this is actually great news as i probably haven’t had real lactic acid build up for two years!!! and i know when i need to rest instead of finding out a day or two later!!
anyways the other good news is that today i stood up and walked around and did things and my heart rate barely went near 100!!! previously standing ip guaranteed a jump to 120-140. i will have to see more closely but i am cautiously optimistic.
also i feel like i didn’t bomb my coding interview on friday.


