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#CRISPR
Gift Article: #CRISPR #SickleCellAnemia F.D.A. Approves Sickle Cell Treatments, Including One That Uses CRISPR
People with the genetic disease have new opportunities to eliminate their symptoms, but the treatments come with obstacles that limit their reach. https://www.nytimes.com/2023/12/08/health/fda-sickle-cell-crispr.html?unlocked_article_code=1.EU0.Fnvk.b8jk5ADO5FSK&hpgrp=k-abar&smid=url-share
While CRISPR is an amazing biological system, it is far from the only one. Among the dozens that have since been identified in bacteria, what about other organisms?
MIT and Harvard scientists have described the first such RNA-guided programmable system in eukaryotes based on the protein Fanzor.
Its compact complexity may make it more suitable for use in humans and other eukaryotes.
We've got some more disease-resistant rice!
UC Davis and many international scientists have used CRISPR to create a new cultivar that is broadly resistant to many diseases.
The gene Resistance To Blast 1 (RBL1), when knocked out, improved resistance, but lowered yields 20 fold. So a mutated allele was made instead to keep the benefits and lose the downsides.