so I said that one of Wren's special interests is murder, but it's probably more accurately described as absence, and the intentional creation of it. all things have a place in the world, however small - there are always consequences to the removal of something.
this is a big part of why she ends up studying a thing that does not exist, at a place that does not exist
I feel too that Wren has a good working relationship with Selcouth. In addition to also being a Neathy chemist, they work with irrigo on a regular basis and have to shape their whole life around the fact that their memory is - to say the least - deeply unreliable.
Sel's interest is less absence itself, and more how one can reliably extrapolate from what exists to determine what is missing, what once existed; to possibly, in turn, understand what might become. (Chthonosophy, possibly! We'll have to see how it's actually used come Firmament.) It's not quite the same field as hers, but it's very, very close.
...also, they're just both prone to exasperation over similar things