blender is one of the few softwares that remain fully functional at a resolution of 320x240, since it lets you set the interface scale all the way down to 0.5

this isn't that useful in this day and age with screens having more pixels than ever, but I remember finding it really nice when goofing off in blender on a 1024x600 Intel(R) Atom(TM) Eee PC R101X instead of paying attention in class