Here are some mods that are making it easier for me to play Stardew with my chronic hand pain!
CJB Cheats Menu - The ultimate mod, tbh. You can simplify or just eliminate some of the repetitive tasks you'd rather not do. Turn on "Harvest With Scythe" for much much much easier harvesting. You can also use it to TELEPORT. This thing... does a lot of things. Just try it out!
CJB Item Spawner - For when you'd rather save your hand power and not collect x number of y item. Great way to cheat your way past things you'd rather not spend limited energy on.
Mouse Move Mode - Move by pointing and clicking! Plays well with other control schemes if you want to mix it up. I use mouse move mode in conjunction with my controller.
Tool Smart Switch - Eliminates a lot of extra button pressing. You'll want to set up the toggle key because sometimes it can be a hindrance in the mines when you're trying to get to an enemy that's behind a bunch of rocks.
Yet Another Jump Mod - Save yourself some running around AND no more double button press to open and then close fence gates. You'll probably need to tweak it in the mod menu at first. VERY adjustable.